By Dr. Tatiana Khrom, Khrom Dermatology & Aesthetics, serving Brighton Beach, Sheepshead Bay, and the greater Brooklyn area
Most patients don’t think about collagen until they notice they’ve lost some of it. By the time lifting or laxity becomes visible, skin has already been losing structural support for years. Prejuvenation is the idea of addressing that earlier, while skin can still respond well to a collagen-stimulating treatment. Here’s what the published evidence actually shows about Sofwave, the technology we use for it.
Why We Start With the Evidence, Not the Trend
Prejuvenation gets talked about often, but not every device marketed for it has data behind it. Our standard for any skin-tightening technology is published, peer-reviewed research and clear FDA indications, not just a marketing claim. Sofwave meets that standard, which is why it’s part of our practice.
How Sofwave Works
Sofwave uses SUPERB (Synchronous Ultrasound Parallel Beam) technology to deliver controlled heat precisely at 1.5mm in the mid-dermis, where collagen, elastin, and hyaluronic acid are actively produced. An integrated cooling system called Sofcool protects the skin’s surface throughout treatment.
The clinical evidence behind Sofwave includes:
- 40+ peer-reviewed publications
- 68% average collagen increase confirmed by biopsy (Suh et al., 2025)
- 33% average elastin increase confirmed by biopsy (Suh et al., 2025)
- Documented stimulation of hyaluronic acid production in the dermis
- 1 million+ treatments worldwide, no fat atrophy events reported in published data
- 7 specific FDA aesthetic clearances
- Results lasting 12 months or longer from a single session
Common Assumptions vs. What the Research Shows
| Common Assumption | What the Published Research Shows |
|---|---|
| Any skin-tightening device works about the same. | Biopsy-confirmed data is specific to each technology. Sofwave’s 68% average collagen and 33% average elastin increases (Suh et al., 2025) are tied to its specific depth and mechanism, not a category-wide result. |
| You should wait until laxity is noticeable to start treatment. | Sofwave is FDA-cleared across 7 specific aesthetic indications, including facial lines and wrinkles, which fits patients addressing early changes rather than waiting for more advanced laxity. |
| Ultrasound skin tightening carries meaningful fat-loss risk. | Sofwave targets the mid-dermis at 1.5mm, above the fat layer. Across 1 million+ treatments worldwide, no fat atrophy events have been reported in published data. |
| Results fade within a few months. | Clinical data shows results lasting 12 months or longer from a single treatment session. |
Who Prejuvenation With Sofwave Is For
Sofwave may be worth discussing at your next visit if you:
- Are starting to notice early changes in skin quality and want to address it before laxity becomes pronounced
- Want a treatment backed by published, biopsy-confirmed evidence rather than general marketing claims
- Have mild to moderate skin laxity already present in the face, neck, or body
- Want little to no downtime
What to Expect With Sofwave at Khrom Dermatology & Aesthetics
Treatment takes 30 to 90 minutes depending on the areas addressed. A cold air stream is used to keep the treatment comfortable, along with the option to add pro-nox laughing gas for maximum relaxation. Most patients describe the sensation as brief pulses of warmth as the ultrasound energy is delivered. There is little to no downtime, though temporary redness or mild swelling can occur for a few hours.
- Weeks 8 to 12: Noticeable lifting and tightening as new collagen matures
- Months 3 to 6: Full results become visible as collagen remodeling progresses
- 12 months and beyond: Results lasting a year or longer from a single session
Frequently Asked Questions
Q: Why start a treatment like Sofwave before signs of aging are obvious?
A: Collagen and elastin decline starting in a person’s twenties, long before lifting or laxity becomes visible. Sofwave stimulates both at a stage when skin can still respond well, which is the idea behind prejuvenation: supporting skin quality early rather than waiting to address more advanced laxity later.
Q: What evidence supports Sofwave’s results?
A: Sofwave is backed by 40+ peer-reviewed publications, including biopsy-confirmed data showing a 68% average increase in collagen and a 33% average increase in elastin (Suh et al., 2025), along with documented stimulation of hyaluronic acid production.
Q: What is Sofwave FDA-cleared to treat?
A: Sofwave has 7 specific FDA aesthetic clearances, including eyebrow lifting, submental and neck lifting, facial lines and wrinkles, cellulite reduction, acne scar improvement, and arm skin laxity.
Q: Is Sofwave safe for the facial fat compartments?
A: Yes. Sofwave targets the mid-dermis at 1.5mm, above the fat layer. Across 1 million+ treatments, no fat atrophy events have been reported in published data.
Q: How long do results last?
A: Results can last 12 months or longer from a single treatment session, with full results typically visible within 3 to 6 months.
Q: Is there downtime after Sofwave?
A: Little to none. Most patients return to their normal activities immediately, though temporary redness or mild swelling can occur for a few hours.
Q: Who is a good candidate for prejuvenation with Sofwave?
A: Patients in their late twenties through forties who want to maintain skin quality before visible laxity sets in, as well as patients with mild to moderate laxity already present, are good candidates. A consultation with the Khrom Dermatology & Aesthetics team will confirm whether Sofwave fits individual goals.
Schedule Your Consultation in South Brooklyn or Cobble Hill
If you’d like to talk through whether Sofwave fits your goals, we’d love to meet with you. Every consultation at Khrom Dermatology & Aesthetics starts with an honest, evidence-based assessment from our dermatology team.
Schedule your consultation with Khrom Dermatology & Aesthetics today.
2797 Ocean Pkwy, 3rd Floor, Brooklyn, NY 11235




